Micky van de Ven Double Ends Everton's Run at New Home Ground
The Dutch defender emerged as the initial backline player to score two goals in a Premier League match for Spurs since Jan Vertonghen in spring 2013.
At a glance
Micky Van de Ven nods into the net two times in first half
Everton's defender has goal ruled after VAR review
Senegalese midfielder nets final goal in 89th minute
The defeat is Everton's initial at their new ground
The Tottenham defender scored on two occasions as Tottenham prolonged their winning streak on the road in the Premier League and handed Everton their initial loss at Hill Dickinson Stadium.
The Toffees were undefeated in their last five matches at their new ground at Bramley-Moore Dock, having departed Goodison Park behind after more than a century at the conclusion of last season.
But Spurs captain the Dutchman struck on two occasions from set-pieces in the first half to place their impressive record at risk, and they were failed to turn it around before the midfielder - set up by ex-Everton forward Richarlison - nodded in a third to seal the victory.
The Everton defender believed he had levelled the tally a short while after the defender's first goal, glancing a powerful header past the Spurs keeper from an Everton corner.
The Portuguese striker, meanwhile, failed to convert a handful of opportunities, while the Italian goalkeeper made a series of fine saves to ensure the London club went five matches on the road unbeaten in the Premier League.
But the video assistant referee stepped in, instructing the match official to review the goal on the screen and the official ruled that Jack Grealish and the attacker were in an illegal position and had impeded with the Spurs keeper.
This victory elevates the manager's team into third place in the division, five points off local foes and table-toppers the Gunners.
Everton stay 14th and are half a dozen points clear of the relegation zone.
Tottenham analysis: The defender excels in role at each end of pitch
After a drab weekday performance in the Champions League against Monaco, where they mustered a only attempts on target, Frank chose Randal Kolo Muani in attack instead of former Toffees player the Brazilian.
The summer signing was unable to make much of an impact before being replaced for Richarlison after an hour on the pitch, but it turns out he proved unnecessary in the final outcome.
Centre-back the Dutchman transformed into an attacking force to be reckoned with.
Spurs' opening strike came from a well-worked set-piece play, with Rodrigo Bentancur directing the ball back across the face of goal for an free Van de Ven to score.
And Ven de Ven - stepping up as captain in the Argentine's unavailability - added his next goal in added time as he rose above the England keeper to nod in.
Van de Ven was equally impressive in defensive duties, partnering well with Kevin Danso as the duo handled excellently with the 34 crosses sent their way by Everton.
Toffees breakdown: Toffees lacking finishing touch
Everton's new home had been a happy hunting ground, but it seems the novelty may have faded somewhat and supporters flocked to the exits after the midfielder's final goal for Spurs.
The break in the team's winning streak at home will not be a massive concern for David Moyes, but their attacking woes will be.
The forward and the other striker - the Everton's two established strikers - had scored only one league goal combined before the weekend's outing.
And they were unable to contribute to that poor tally on a damp and dreary evening on Merseyside.
The striker's form was epitomized when he chose to bicycle-kick a clear chance from near the goal, even with having room and time to reposition for a more conventional shot that would have tested Vicario.
Barry, as well, was unable to influence the game after replacing the starter in the 65th minute.
It was not for a lack of chance. The majority of Everton's attacks came through Grealish and the forward, who tirelessly whipped dangerous balls into the Tottenham penalty area.
What next for these two sides?
The Toffees: Moyes' men travel to Sunderland in the top flight on Monday, 3 November at 8 PM.
Spurs: Spurs go to St James' Park on late October for their next round Carabao Cup match against Newcastle.